Liverpool and fellow English sides Manchester City, Chelsea and Tottenham will find out who they face in the last 16 of the Champions League when the draw takes place at 11:00 GMT in Nyon on Monday.
Holders Liverpool and City will go into the draw as seeds.
Barcelona, Bayern Munich and Real Madrid are among the other clubs to reach the knockout phase.
This season’s final is on 30 May at the Ataturk Stadium in Istanbul.
Arsenal, Celtic, Manchester United, Wolves and Rangers will find out their Europa League last-32 opponents when that draw takes place at 12:00 GMT on Monday.
How will the draw work?
The teams will be divided into two pots, with the first consisting of all of the group-stage winners, the other all the runner-ups.
No team can face another club from the same country or a team that they played during the group stage.
That means that Liverpool could not face Tottenham, Chelsea or Napoli. Manchester City would also avoid their fellow English clubs and Atalanta.
The seeded group winners will play away from home first, ensuring they have home advantage in the second leg.
The last-16 ties begin on 18-19 February and 25-26 February, with the second legs scheduled to take place on 10-11 March and 17-18 March.
Who is in which pot?
Barcelona, Bayern Munich, Juventus, Liverpool, Manchester City, RB Leipzig, Paris St-Germain, Valencia
Atalanta, Atletico Madrid, Borussia Dortmund, Chelsea, Lyon, Napoli, Real Madrid, Tottenham
Who could English clubs face?
Liverpool: Atalanta, Atletico Madrid, Borussia Dortmund, Lyon, Real Madrid
Manchester City: Atletico Madrid, Borussia Dortmund, Lyon, Napoli, Real Madrid
Chelsea: Barcelona, Bayern Munich, Juventus, RB Leipzig, Paris St-Germain
Tottenham: Barcelona, Juventus, RB Leipzig, Paris St-Germain, Valencia
Champions League calendar
16 December: Last-16 draw
18, 19, 25, 26 February: Last-16 first legs
10, 11, 17, 18 March: Last-16 second legs
20 March: Quarter-finals and semi-finals draw
7, 8 April: Quarter-finals first leg
14, 15 April: Quarter-finals second leg
28, 29 April: Semi-finals first leg
5, 6 May: Semi-finals second leg
30 May: Final