Team Sky chief Sir Dave Brailsford will appear on Monday in front of a Culture, Media and Sport select committee on sport’s fight against doping.
MPs are expected to ask him about British cyclist Sir Bradley Wiggins’ therapeutic use exemptions (TUEs).
They allow the use of banned substances if athletes have genuine medical need.
Brailsford is also expected to be asked about an allegation in the Daily Mail about a medical package delivered to Team Sky in France in June 2011.
He has previously refused to comment on the contents of the alleged delivery, said to have been made on the day Wiggins won the Criterium du Dauphine in La Toussuire.
Team Sky have said they conducted an internal review and were “confident there has been no wrongdoing”.
Brailsford will be one of six witnesses – along with British Cycling technical director and Team Sky coach Shane Sutton, and World Anti-Doping Agency president Sir Craig Reedie – appearing at the hearing.
- Wiggins: No unfair advantage from drug
- Brailsford: Team Sky ‘do not cross the line’
- Ex-Team Sky rider questions TUE stance
- Ukad investigating cycling wrongdoing
Sports minister Tracey Crouch told BBC 5 live’s Sportsweek programme she would be watching with “great interest”.
“He will be asked some extremely important questions and he will have to justify himself and his actions, and it’s not for me as sports minister to say otherwise,” said Crouch.
Wiggins, a five-time Olympic champion, was granted a TUE to take anti-inflammatory drug triamcinolone before the 2011 Tour de France, his 2012 Tour win and the 2013 Giro d’Italia.
His use of the drug, which treats allergies and respiratory issues, was released by Russian computer hackers known as Fancy Bears.
Wiggins’ TUEs were approved by British authorities and cycling’s world governing body the UCI, and there is no suggestion either the 36-year-old or former employers Team Sky have broken any rules.
Former Team Sky cyclist Jonathan Tiernan-Locke has said painkiller Tramadol was “freely offered” when he was riding for Great Britain at the 2012 World Championships.
British Cycling, the national governing body, put the allegation to the medic in question, doctor Richard Freeman, on the BBC’s behalf. He denied it.
UK Anti-Doping says it is investigating allegations of wrongdoing in cycling.